Link to K08E3.6Link to K08E3.7.1Link to K08E3.7.2RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to Y102A5C.35geneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: MV_SV:mv_K08E3.6 Ace View of MV_SV:mv_K08E3.6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  K08E3.6 (cyk-4)
Description of "K08E3.6"  cyk-4 encodes a GTPase activating protein (GAP) for the Rho family of GTPases that, together with ZEN-4, is sufficient to promote the formation of the large bundles of microtubules that form the central spindle during anaphase, and is required for fertility and coordinated locomotion postembryonically; localizes to the central spindle during anaphase interdependently with ZEN-4, and interacts with ZEN-4 in vitro and in vivo.
KOG Annotation  GTPase-activating protein
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1917
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "K08E3.6" Links  Wormbase NCBI
MV_SV:mv_K08E3.6 Phenotypes Help with Phenotypes
Adult  Pvl penetrance is less than 90%
Rup penetrance is less than 90%
Ste
Unc
MV_SV:mv_K08E3.6 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_K08E3.6 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of K08E3.6 Browse using GBrowse
Gene Graph