Link to R06C7.7.1Link to R06C7.7.2RNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: MV_SV:mv_R06C7.7 Ace View of MV_SV:mv_R06C7.7
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  R06C7.7 (lin-61)
Description of "R06C7.7"  lin-61 encodes a protein that contains mbt repeats and has similarity to the Drosophila Polycomb group protein Sex Comb on Midleg and human protein H-l-(3)mbl-like; by homology, LIN-61 is predicted to function as part of a transcriptional regulatory complex that may play a role in transcriptional repression during development; loss of lin-61 activity via RNAi and forward mutations indicates that LIN-61 is required for: 1) genome stability in the soma and germline, and 2) postembryonic developmental processes such as vulval development, in which lin-61 acts as a class B synthetic multivulval (SynMuv) gene.
KOG Annotation  Polycomb group protein SCM/L(3)MBT (tumor-supressor in Drosophila and humans)
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1787
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "R06C7.7" Links  Wormbase NCBI
MV_SV:mv_R06C7.7 Phenotypes Help with Phenotypes
Phenotype  WTRNAi did not cause viable post-embryonic phenotype
MV_SV:mv_R06C7.7 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_R06C7.7 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of R06C7.7 Browse using GBrowse
Gene Graph