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RNAi Experiment: MV_SV:mv_R11E3.6 Ace View of MV_SV:mv_R11E3.6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  R11E3.6 (eor-1)
Description of "R11E3.6"  eor-1 encodes an ortholog of the human BTB/zinc-finger transcription factor PLZF (OMIM:176797), which is is found as a retinoic acid receptor alpha (RARA) fusion in acute promyelocytic leukemia (APL); EOR-1 positively regulates RAS/RAF-mediated signalling during excretory system development, as well as RAS/RAF- and WNT-mediated signalling during P12 fate specification; EOR-1 may function with EOR-2 and Hox genes to control the expression of Ras- and Wnt-responsive genes.
KOG Annotation  Zn-finger
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 2412
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "R11E3.6" Links  Wormbase NCBI
MV_SV:mv_R11E3.6 Phenotypes Help with Phenotypes
Phenotype  WTRNAi did not cause viable post-embryonic phenotype
MV_SV:mv_R11E3.6 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_R11E3.6 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of R11E3.6 Browse using GBrowse
Gene Graph