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RNAi Experiment: MV_SV:mv_T20B12.8 Ace View of MV_SV:mv_T20B12.8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T20B12.8 (hmg-4)
Description of "T20B12.8"  hmg-4 encodes a protein with strong similarity to the highly conserved high mobility group protein SSRP1 (structure-specific DNA recognition protein); by homology, HMG-4 is predicted to be a member of the FACT (facilitates chromatin transcription) complex that functions as a transcription elongation factor; RNAi experiments indicate that hmg-4 is required for locomotion and larval development, and required redundantly with hmg-3, its paralog, for embryonic development.
KOG Annotation  Nucleosome-binding factor SPN, POB3 subunit
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1986
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.945
Wormbase (BLAST) RNAi primary
External "T20B12.8" Links  Wormbase NCBI
Gene Inhibited  C32F10.5 (hmg-3)
Description of "C32F10.5"  Associated GO Term : DNA binding
KOG Annotation  Nucleosome-binding factor SPN, POB3 subunit
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 115
Relative score: 0.058 (Best raw score= for Gene )
Specificity index: 0.055
Wormbase (BLAST) RNAi secondary
External "C32F10.5" Links  Wormbase NCBI
MV_SV:mv_T20B12.8 Phenotypes Help with Phenotypes
Adult  Pvl penetrance is less than 90%
Ste
Phenotype  Unclassified slim morphology
MV_SV:mv_T20B12.8 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_T20B12.8 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of T20B12.8 Browse using GBrowse
Gene Graph
Gene Plot of C32F10.5 Browse using GBrowse
Gene Graph