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RNAi Experiment: MV_SV:mv_T22A3.3 Ace View of MV_SV:mv_T22A3.3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T22A3.3 (lst-1)
Description of "T22A3.3"  lst-1 encodes an unfamiliar protein with no known homologs outside of nematodes; in two-hybrid assays, LST-1 does not interact with control baits, but does interact with GPA-6, LAG-1, MPK-1 and K06A1.4, suggesting broad or unspecific interaction activity; however, T22A3.3 solely binds the normal form of GPA-6, without binding its constitutively active mutant form; LST-1 is expressed in head neurons (AWB, ADF, ASG, various interlabial sensory), socket cells, sheath cells in the nose tip, pharyngeal muscle, and intestine; LST-1 has no obvious function or phenotype in RNAi assays.
Evidence for Inhibition 
Sliding Window Raw score: 1026
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "T22A3.3" Links  Wormbase NCBI
MV_SV:mv_T22A3.3 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  Unclassified reduced brood size
MV_SV:mv_T22A3.3 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_T22A3.3 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of T22A3.3 Browse using GBrowse
Gene Graph