Description of "T22A3.3" |
lst-1 encodes an unfamiliar protein with no known homologs outside of nematodes; in two-hybrid assays, LST-1 does not interact with control baits, but does interact with GPA-6, LAG-1, MPK-1 and K06A1.4, suggesting broad or unspecific interaction activity; however, T22A3.3 solely binds the normal form of GPA-6, without binding its constitutively active mutant form; LST-1 is expressed in head neurons (AWB, ADF, ASG, various interlabial sensory), socket cells, sheath cells in the nose tip, pharyngeal muscle, and intestine; LST-1 has no obvious function or phenotype in RNAi assays. |