RNAi Experiment: MV_SV:mv_T24D1.1 |
Ace View of MV_SV:mv_T24D1.1
|
Genes Inhibited |
|
Gene Inhibited |
T24D1.1 (sqv-5) |
Description of "T24D1.1" |
sqv-5 encodes a chondroitin synthase that both initiates and elongates chondroitin chains (unlike human chondroitin synthase, which only elongates them); SQV-5 is required for cytokinesis (e.g., at the one-cell embryo stage), gonad migration, and vulval morphogenesis (by expanding the extracellular space of the vulva in L4 larvae); the common requirement for SQV-5 in both processes may be to promote filling an extracellular space with fluid (either in the eggshell, or underneath the L4 cuticle); SQV-5 colocalizes with SQV-1 at punctate foci (probably the Golgi apparatus) in the cytoplasm of the vulva, the uterus and oocytes; SQV-5 is most similar to human chondroitin synthase (KIAA0990) and Drosophila CG9220. |
Evidence for Inhibition |
Sliding Window |
Raw score: 2069
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
|
External "T24D1.1" Links |
|
MV_SV:mv_T24D1.1 Phenotypes |
|
|
Phenotype |
Unclassified
reduced brood size
|
MV_SV:mv_T24D1.1 Experiment Details |
Ace View |
Laboratory |
MV |
RNAi Reagent & Type |
mv_T24D1.1 (ORFeome_reagent) |
Remark |
bacterial-feeding RNAi began at the L1 larval stage |
Reference |
Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...." |
Delivery Method |
Bacterial_feeding |
Date |
2004-9-01 |
Gene Plot of T24D1.1 |
Browse using GBrowse
|
|