Link to T24D1.1bLink to T24D1.1aLink to T24D1.2.1Link to T24D1.2.2RNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
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RNAi Experiment: MV_SV:mv_T24D1.1 Ace View of MV_SV:mv_T24D1.1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T24D1.1 (sqv-5)
Description of "T24D1.1"  sqv-5 encodes a chondroitin synthase that both initiates and elongates chondroitin chains (unlike human chondroitin synthase, which only elongates them); SQV-5 is required for cytokinesis (e.g., at the one-cell embryo stage), gonad migration, and vulval morphogenesis (by expanding the extracellular space of the vulva in L4 larvae); the common requirement for SQV-5 in both processes may be to promote filling an extracellular space with fluid (either in the eggshell, or underneath the L4 cuticle); SQV-5 colocalizes with SQV-1 at punctate foci (probably the Golgi apparatus) in the cytoplasm of the vulva, the uterus and oocytes; SQV-5 is most similar to human chondroitin synthase (KIAA0990) and Drosophila CG9220.
Evidence for Inhibition 
Sliding Window Raw score: 2069
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "T24D1.1" Links  Wormbase NCBI
MV_SV:mv_T24D1.1 Phenotypes Help with Phenotypes
Phenotype  Unclassified reduced brood size
MV_SV:mv_T24D1.1 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_T24D1.1 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of T24D1.1 Browse using GBrowse
Gene Graph