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RNAi Experiment: MV_SV:mv_T28F12.2a Ace View of MV_SV:mv_T28F12.2a
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T28F12.2 (unc-62)
Description of "T28F12.2"  unc-62 encodes a Meis-class homeodomain protein required for posterior embryonic morphogenesis, male tail morphogenesis, commissure formation by VD and DD motor neurons, vulval morphogenesis, and normal locomotion; UNC-62 is orthologous to Drosophila HOMOTHORAX; both maternal-effect unc-62 alleles and the zygotic lethal unc-62(s472) allele phenotypically resemble mutations of the caudal ortholog pal-1; RNAi of the Pbc-class ceh-20 and ceh-40 homeodomain genes strongly enhances the hypomorphic unc-62(e644) allele to give either a strong loss-of-function or null-like phenotype, while overexpression of ceh-20 enhances the lethality of some unc-62 alleles.
Evidence for Inhibition 
Sliding Window Raw score: 860
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "T28F12.2" Links  Wormbase NCBI
MV_SV:mv_T28F12.2a Phenotypes Help with Phenotypes
Adult  Egl
Ooc
Pvl penetrance is less than 90%
Unc penetrance is less than 90%
Phenotype  Unclassified reduced brood size
MV_SV:mv_T28F12.2a Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_T28F12.2a (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of T28F12.2 Browse using GBrowse
Gene Graph