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RNAi Experiment: MV_SV:mv_VF36H2L.1 Ace View of MV_SV:mv_VF36H2L.1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  VF36H2L.1 (aph-1)
Description of "VF36H2L.1"  aph-1 encodes an unfamiliar protein predicted to have seven transmembrane domains; APH-1 is a component of the GLP-1/LIN-12 (Notch) pathway, is required maternally for embryonic viability, and also affects morphogenesis, egg laying, germ line proliferation, and translocation of APH-2 to the cell surface; with PEN-2, APH-1 is required for Notch pathway signaling, gamma-secretase cleavage of beta-amyloid precursor protein, and presenilin protein accumulation.
KOG Annotation  Predicted membrane protein
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 840
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "VF36H2L.1" Links  Wormbase NCBI
MV_SV:mv_VF36H2L.1 Phenotypes Help with Phenotypes
Phenotype  WTRNAi did not cause viable post-embryonic phenotype
MV_SV:mv_VF36H2L.1 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_VF36H2L.1 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of VF36H2L.1 Browse using GBrowse
Gene Graph