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RNAi Experiment: MV_SV:mv_W02G9.1 Ace View of MV_SV:mv_W02G9.1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  W02G9.1 (ndx-2)
Description of "W02G9.1"  ndx-2 encodes a NUDIX hydrolase; by sequence comparison, NDX-2 is predicted to be orthologous to human NUDT5 which, in vitro, possesses ADP-sugar diphosphatase activity; in C. elegans, loss of ndx-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways.
KOG Annotation  Nucleoside diphosphate-sugar hydrolase of the MutT (NUDIX) family
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 606
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "W02G9.1" Links  Wormbase NCBI
MV_SV:mv_W02G9.1 Phenotypes Help with Phenotypes
Phenotype  WTRNAi did not cause viable post-embryonic phenotype
MV_SV:mv_W02G9.1 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_W02G9.1 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of W02G9.1 Browse using GBrowse
Gene Graph