RNAi Experiment: MV_SV:mv_Y111B2G.i |
Ace View of MV_SV:mv_Y111B2G.i
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Genes Inhibited |
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Gene Inhibited |
Y111B2A.18 (rsp-3) |
Description of "Y111B2A.18" |
rsp-3 encodes a putative ortholog of human SF2/ASF and member of the SR protein family of nuclear phosphoproteins that are required for constitutive splicing and influence alternative splicing regulation; rsp-3 affects the development of oocytes together with rsr-1, and is required for late embryonic viability; SPK-1 binds directly to and phosphorylates the RS domain of RSP-3 in vitro and the mRNA of rsp-3 is predominantly expressed in the germline. |
KOG Annotation  |
Alternative splicing factor ASF/SF2 (RRM superfamily)
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Evidence for Inhibition |
Sliding Window |
Raw score: 711
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "Y111B2A.18" Links |
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MV_SV:mv_Y111B2G.i Phenotypes |
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Embryonic |
Emb Penetrance None reported |
Larval |
Lva
phenotype observed among F1 progeny of treated animals
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MV_SV:mv_Y111B2G.i Experiment Details |
Ace View |
Laboratory |
MV |
RNAi Reagent & Type |
mv_Y111B2G.i (ORFeome_reagent) |
Remark |
bacterial-feeding RNAi began at the L1 larval stage |
Reference |
Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...." |
Delivery Method |
Bacterial_feeding |
Date |
2004-9-01 |
Gene Plot of Y111B2A.18 |
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