Ace View of MV_SV:mv_Y38C1AB.4 | ||||||
Gene Inhibited | Y38C1AB.8 (frm-5) | |||||
Description of "Y38C1AB.8" | frm-5 encodes a protein that contains a FERM (Band 4.1-ezrin-radixin-moesin) domain near the center of the molecule and two C-terminal PDZ domains; by homology, FRM-5 is predicted to function as a membrane-cytoskeleton linker protein that plays a role in cell adhesion, migration, or organization of cell surface structures; however, as loss of frm-5 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of FRM-5 in C. elegans development and/or behavior is not yet known; the FRM-5 FERM and PDZ domains are most similar to those found in cytoplasmic protein tyrosine phosphatases, even though FRM-5 does not appear to be a phosphatase. | |||||
KOG Annotation  | Membrane-associated protein tyrosine phosphatase PTP-BAS and related proteins, contain FERM domain |
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Evidence for Inhibition |
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External "Y38C1AB.8" Links | ![]() ![]() |
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Gene Inhibited | Y38C1AB.4 | |||||
Description of "Y38C1AB.4" | Associated GO Term : cytoskeleton | |||||
KOG Annotation  | Membrane-associated protein tyrosine phosphatase PTP-BAS and related proteins, contain FERM domain |
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Evidence for Inhibition |
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External "Y38C1AB.4" Links | ![]() ![]() |
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Phenotype | WTRNAi did not cause viable post-embryonic phenotype |
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Laboratory | MV | |||||
RNAi Reagent & Type | mv_Y38C1AB.4 (ORFeome_reagent) | |||||
Remark | bacterial-feeding RNAi began at the L1 larval stage | |||||
Reference | Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...." | |||||
Delivery Method | Bacterial_feeding | |||||
Date | 2004-9-01 | |||||
Gene Plot of Y38C1AB.8 | ||||||
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Gene Plot of Y38C1AB.4 | ||||||
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