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RNAi Experiment: MV_SV:mv_Y48G1A.d Ace View of MV_SV:mv_Y48G1A.d
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y48G1A.5 (imb-5)
Description of "Y48G1A.5"  imb-5 encodes an importin-beta-like protein orthologous to mammalian CAS proteins (cellular apoptosis susceptibility) and Saccharomyces cerevisiae CSE1 (chromosome segregation 1); IMB-5 is predicted to function in nuclear transport of proteins required for mitotic progression or apoptosis as well as in re-export of importin-alpha, a nuclear import protein; in C. elegans, IMB-5 is essential for embryogenesis and required for normal pronuclear envelope dynamics, and may also play a role in vulval morphogenesis.
KOG Annotation  Nuclear export receptor CSE1/CAS (importin beta superfamily)
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1537
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y48G1A.5" Links  Wormbase NCBI
MV_SV:mv_Y48G1A.d Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Larval  Lva phenotype observed among F1 progeny of treated animals
Adult  Sck
Phenotype  Unclassified reduced brood size
MV_SV:mv_Y48G1A.d Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_Y48G1A.d (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of Y48G1A.5 Browse using GBrowse
Gene Graph