RNAi Card Page

RNAi Experiment: MV_SV:mv_Y54E10BL.2

Ace View of MV_SV:mv_Y54E10BL.2

Genes Inhibited

Gene Inhibited

H06A10.2 (col-185)

Description of "H06A10.2"

Associated GO Term : structural constituent of cuticle

Evidence for Inhibition

Sliding Window

Raw score: 196
Relative score: 0.247 (Best raw score= for Gene )
Specificity index: 0.057

External "H06A10.2" Links

Gene Inhibited

F56B3.1 (col-103)

Description of "F56B3.1"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 278
Relative score: 0.351 (Best raw score= for Gene )
Specificity index: 0.081

External "F56B3.1" Links

Gene Inhibited

T13B5.4 (col-40)

Description of "T13B5.4"

col-40 encodes a cuticle collagen protein that belongs to the col-6 cuticle collagen family; col-40 transcript is present in L1 larvae and at the L2d-dauer molt.

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 122
Relative score: 0.154 (Best raw score= for Gene )
Specificity index: 0.036

External "T13B5.4" Links

Gene Inhibited

Y54E10BL.2 (col-48)

Description of "Y54E10BL.2"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window	Raw score: 792 Relative score: 1 (This gene has the best score for this RNAi reagent) Specificity index: 0.232
Wormbase (BLAST)	RNAi primary

External "Y54E10BL.2" Links

Gene Inhibited

EGAP7.1 (dpy-3)

Description of "EGAP7.1"

dpy-3 encodes a cuticular collagen; along with dpy-2, dpy-7, dpy-8, and dpy-10, dpy-3 is required postembryonically for annular furrow formation and/or maintenance; specifically, DPY-3 activity is required for proper assembly of the DPY-7 collagen into the mature extracellular matrix; during each cuticle synthetic period, dpy-3 mRNA is expressed approximately four hours prior to the secretion of new cuticle.

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 378
Relative score: 0.477 (Best raw score= for Gene )
Specificity index: 0.111

External "EGAP7.1" Links

Gene Inhibited

F23H12.4 (sqt-3)

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 149
Relative score: 0.188 (Best raw score= for Gene )
Specificity index: 0.044

External "F23H12.4" Links

Gene Inhibited

T28F2.6 (col-50)

Description of "T28F2.6"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 292
Relative score: 0.369 (Best raw score= for Gene )
Specificity index: 0.086

External "T28F2.6" Links

Gene Inhibited

T21B4.2 (col-85)

Description of "T21B4.2"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 113
Relative score: 0.143 (Best raw score= for Gene )
Specificity index: 0.033

External "T21B4.2" Links

Gene Inhibited

F54B11.2 (col-44)

Description of "F54B11.2"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 242
Relative score: 0.306 (Best raw score= for Gene )
Specificity index: 0.071

External "F54B11.2" Links

Gene Inhibited

C09G5.5 (col-80)

Description of "C09G5.5"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 198
Relative score: 0.25 (Best raw score= for Gene )
Specificity index: 0.058

External "C09G5.5" Links

Gene Inhibited

F01G12.5 (let-2)

Description of "F01G12.5"

let-2 encodes an alpha-2 type IV collagen, probably most closely equivalent to the human gene COL4A2 (OMIM:120090) on the basis of biological function; LET-2 is required for embryonic development and is a component of the basement membrane between muscle and hypodermis; LET-2 interacts with UNC-105, a mechanosensory ion channel of the degenerin ion channel superfamily that is expressed in muscle and required for normal growth, muscle contraction, and muscle organization.

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 581
Relative score: 0.711 (Best raw score= for Gene )
Specificity index: 0.165

External "F01G12.5" Links

Gene Inhibited

T28F2.8 (col-51)

Description of "T28F2.8"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins