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RNAi Experiment: MV_SV:mv_Y54E5B.3 Ace View of MV_SV:mv_Y54E5B.3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y54E5B.3 (let-49)
Description of "Y54E5B.3"  let-49 encodes a putative mediator complex subunit zygotically required for postembryonic development and viability past larval stages, while being maternally required for germline and embryonic development; LET-49 is an ortholog of human CRSP9 (OMIM:605045) and of S. cerevisiae Med7p; Med7p is a component of a mediator complex that serves as a transcriptional coactivator, while CRSP9 mediates transcriptional activation by Sp1.
KOG Annotation  Transcriptional coactivator
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 654
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y54E5B.3" Links  Wormbase NCBI
MV_SV:mv_Y54E5B.3 Phenotypes Help with Phenotypes
Phenotype  WTRNAi did not cause viable post-embryonic phenotype
MV_SV:mv_Y54E5B.3 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_Y54E5B.3 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of Y54E5B.3 Browse using GBrowse
Gene Graph