RNAi Experiment: MV_SV:mv_Y59H11AM.d |
Ace View of MV_SV:mv_Y59H11AM.d
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Genes Inhibited |
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Gene Inhibited |
Y59E9AR.7 |
Description of "Y59E9AR.7" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 140
Specificity index: 0.059 |
Wormbase (BLAST) |
RNAi primary |
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External "Y59E9AR.7" Links |
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Gene Inhibited |
K07F5.2 (msp-10) |
Description of "K07F5.2" |
msp-10 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 62
Relative score: 0.183 (Best raw score= for Gene )
Specificity index: 0.026 |
Wormbase (BLAST) |
RNAi secondary |
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External "K07F5.2" Links |
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Gene Inhibited |
C09B9.6 (msp-55) |
Description of "C09B9.6" |
msp-55 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 163
Relative score: 0.481 (Best raw score= for Gene )
Specificity index: 0.069 |
Wormbase (BLAST) |
RNAi primary |
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External "C09B9.6" Links |
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Gene Inhibited |
K07F5.1 (msp-81) |
Description of "K07F5.1" |
msp-81 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 61
Relative score: 0.18 (Best raw score= for Gene )
Specificity index: 0.026 |
Wormbase (BLAST) |
RNAi secondary |
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External "K07F5.1" Links |
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Gene Inhibited |
F36H12.7 (msp-19) |
Description of "F36H12.7" |
msp-19 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-19 has a homolog in C. briggsae as predicted by the Wobble Aware Bulk Aligner (WABA); the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 114
Specificity index: 0.048 |
Wormbase (BLAST) |
RNAi primary |
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External "F36H12.7" Links |
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Gene Inhibited |
Y59E9AR.1 |
Description of "Y59E9AR.1" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 140
Relative score: 0.413 (Best raw score= for Gene )
Specificity index: 0.059 |
Wormbase (BLAST) |
RNAi primary |
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External "Y59E9AR.1" Links |
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Gene Inhibited |
R13H9.2 (msp-57) |
Description of "R13H9.2" |
msp-57 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 124
Relative score: 0.366 (Best raw score= for Gene )
Specificity index: 0.052 |
Wormbase (BLAST) |
RNAi primary |
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External "R13H9.2" Links |
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Gene Inhibited |
K08F4.8 (msp-38) |
Description of "K08F4.8" |
msp-38 encodes a member of the major sperm protein family; msp-38 has a C. briggsae homolog as predicted by the Wobble Bulk Aware Bulk Aligner (WABA). |
Evidence for Inhibition |
Sliding Window |
Raw score: 70
Relative score: 0.206 (Best raw score= for Gene )
Specificity index: 0.03 |
Wormbase (BLAST) |
RNAi secondary |
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External "K08F4.8" Links |
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Gene Inhibited |
ZK354.5 (msp-51) |
Description of "ZK354.5" |
msp-51 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-51 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 149
Relative score: 0.44 (Best raw score= for Gene )
Specificity index: 0.063 |
Wormbase (BLAST) |
RNAi primary |
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External "ZK354.5" Links |
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Gene Inhibited |
ZK354.10 (msp-58) |
Description of "ZK354.10" |
msp-58 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 146
Specificity index: 0.062 |
Wormbase (BLAST) |
RNAi primary |
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External "ZK354.10" Links |
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Gene Inhibited |
T13F2.10 (msp-79) |
Description of "T13F2.10" |
msp-79 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 59 |
Wormbase (BLAST) |
RNAi secondary |
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External "T13F2.10" Links |
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Gene Inhibited |
F58A6.8 (msp-45) |
Description of "F58A6.8" |
msp-45 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 65
Relative score: 0.192 (Best raw score= for Gene )
Specificity index: 0.027 |
Wormbase (BLAST) |
RNAi secondary |
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External "F58A6.8" Links |
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Gene Inhibited |
R13H9.4 (msp-53) |
Description of "R13H9.4" |
msp-53 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-53 has a C. briggsae homolog as identified by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 114
Relative score: 0.336 (Best raw score= for Gene )
Specificity index: 0.048 |
Wormbase (BLAST) |
RNAi primary |
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External "R13H9.4" Links |
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Gene Inhibited |
ZK354.4 (msp-113) |
Description of "ZK354.4" |
msp-113 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-113 has a C. briggsae homolog as detected by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; the msp-113 promoter region contains two conserved cis elements that are recognition sites for elt-1, a gene that encodes a homolog of the vertebrate GATA transcription factor family; this suggests that a MSP protein is a potential target for ELT-1 in the germ-line; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 190
Relative score: 0.56 (Best raw score= for Gene )
Specificity index: 0.08 |
Wormbase (BLAST) |
RNAi primary |
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External "ZK354.4" Links |
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Gene Inhibited |
ZK354.11 (msp-59) |
Description of "ZK354.11" |
msp-59 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 170
Relative score: 0.501 (Best raw score= for Gene )
Specificity index: 0.072 |
Wormbase (BLAST) |
RNAi primary |
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External "ZK354.11" Links |
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Gene Inhibited |
C04G2.4 (msp-36) |
Description of "C04G2.4" |
msp-36 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family comprises of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSP is involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP assembles into fibrous networks that drives movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 59 |
Wormbase (BLAST) |
RNAi secondary |
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External "C04G2.4" Links |
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Gene Inhibited |
ZK354.1 (msp-65) |
Description of "ZK354.1" |
msp-65 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 146
Relative score: 0.431 (Best raw score= for Gene )
Specificity index: 0.062 |
Wormbase (BLAST) |
RNAi primary |
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External "ZK354.1" Links |
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Gene Inhibited |
Y59H11AM.1 |
Description of "Y59H11AM.1" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 339
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.143 |
Wormbase (BLAST) |
RNAi primary |
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External "Y59H11AM.1" Links |
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Gene Inhibited |
F59A6.8 (msp-71) |
Description of "F59A6.8" |
msp-71 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 106
Relative score: 0.313 (Best raw score= for Gene )
Specificity index: 0.045 |
Wormbase (BLAST) |
RNAi secondary |
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External "F59A6.8" Links |
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Gene Inhibited |
R05F9.13 (msp-31) |
Description of "R05F9.13" |
msp-31 encodes a member of the major sperm protein family; msp-31 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); expression is enriched in sperm. |
Evidence for Inhibition |
Sliding Window |
Raw score: 69
Relative score: 0.204 (Best raw score= for Gene )
Specificity index: 0.029 |
Wormbase (BLAST) |
RNAi secondary |
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External "R05F9.13" Links |
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MV_SV:mv_Y59H11AM.d Phenotypes |
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Phenotype |
WTRNAi did not cause viable post-embryonic phenotype
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MV_SV:mv_Y59H11AM.d Experiment Details |
Ace View |
Laboratory |
MV |
RNAi Reagent & Type |
mv_Y59H11AM.d (ORFeome_reagent) |
Remark |
bacterial-feeding RNAi began at the L1 larval stage |
Reference |
Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...." |
Delivery Method |
Bacterial_feeding |
Date |
2004-9-01 |
Gene Plot of Y59E9AR.7 |
Browse using GBrowse
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Gene Plot of K07F5.2 |
Browse using GBrowse
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Gene Plot of C09B9.6 |
Browse using GBrowse
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Gene Plot of K07F5.1 |
Browse using GBrowse
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Gene Plot of F36H12.7 |
Browse using GBrowse
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Gene Plot of Y59E9AR.1 |
Browse using GBrowse
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Gene Plot of R13H9.2 |
Browse using GBrowse
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Gene Plot of K08F4.8 |
Browse using GBrowse
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Gene Plot of F58A6.8 |
Browse using GBrowse
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Gene Plot of T13F2.10 |
Browse using GBrowse
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Gene Plot of ZK354.10 |
Browse using GBrowse
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Gene Plot of ZK354.5 |
Browse using GBrowse
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Gene Plot of ZK354.4 |
Browse using GBrowse
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Gene Plot of R13H9.4 |
Browse using GBrowse
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Gene Plot of ZK354.11 |
Browse using GBrowse
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Gene Plot of C04G2.4 |
Browse using GBrowse
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Gene Plot of ZK354.1 |
Browse using GBrowse
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Gene Plot of Y59H11AM.1 |
Browse using GBrowse
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Gene Plot of R05F9.13 |
Browse using GBrowse
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Gene Plot of F59A6.8 |
Browse using GBrowse
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