RNAi Experiment: MV_SV:mv_ZC308.1 |
Ace View of MV_SV:mv_ZC308.1
|
Genes Inhibited |
 |
Gene Inhibited |
ZC308.1 (gld-2) |
Description of "ZC308.1" |
gld-2 encodes the catalytic subunit of a cytoplasmic poly(A) polymerase (PAP) associated with P granules in early embryos, which encodes the central catalytic domain but lacks the normal RNA-binding (RRM) domain of eukaryotic PAPs; GLD-2 regulates the switch from mitosis to meiosis in the germline, is necessary for formation of functional sperm or oocytes, requires activation by GLD-3 for PAP activity in vitro, and contains a glutamine/asparagine-rich domain perhaps involved in epigenetic gene control. |
Evidence for Inhibition |
Sliding Window |
Raw score: 2403
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
|
External "ZC308.1" Links |
 |
MV_SV:mv_ZC308.1 Phenotypes |
|
 |
Phenotype |
Unclassified
reduced brood size
|
MV_SV:mv_ZC308.1 Experiment Details |
Ace View |
Laboratory |
MV |
RNAi Reagent & Type |
mv_ZC308.1 (ORFeome_reagent) |
Remark |
bacterial-feeding RNAi began at the L1 larval stage |
Reference |
Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...." |
Delivery Method |
Bacterial_feeding |
Date |
2004-9-01 |
Gene Plot of ZC308.1 |
Browse using GBrowse
|
 |