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RNAi Experiment: MV_SV:mv_ZC308.1 Ace View of MV_SV:mv_ZC308.1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  ZC308.1 (gld-2)
Description of "ZC308.1"  gld-2 encodes the catalytic subunit of a cytoplasmic poly(A) polymerase (PAP) associated with P granules in early embryos, which encodes the central catalytic domain but lacks the normal RNA-binding (RRM) domain of eukaryotic PAPs; GLD-2 regulates the switch from mitosis to meiosis in the germline, is necessary for formation of functional sperm or oocytes, requires activation by GLD-3 for PAP activity in vitro, and contains a glutamine/asparagine-rich domain perhaps involved in epigenetic gene control.
Evidence for Inhibition 
Sliding Window Raw score: 2403
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "ZC308.1" Links  Wormbase NCBI
MV_SV:mv_ZC308.1 Phenotypes Help with Phenotypes
Phenotype  Unclassified reduced brood size
MV_SV:mv_ZC308.1 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_ZC308.1 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of ZC308.1 Browse using GBrowse
Gene Graph