| RNAi Experiment: MV_SV:mv_ZK1251.6 |
Ace View of MV_SV:mv_ZK1251.6
|
| Genes Inhibited |
 |
| Gene Inhibited |
Y59E9AR.7 |
| Description of "Y59E9AR.7" |
Associated GO Term : structural molecule activity |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 68
Specificity index: 0.029 |
| Wormbase (BLAST) |
RNAi secondary |
|
| External "Y59E9AR.7" Links |
  |
| Gene Inhibited |
K07F5.2 (msp-10) |
| Description of "K07F5.2" |
msp-10 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 212
Relative score: 0.625 (Best raw score= for Gene )
Specificity index: 0.089 |
| Wormbase (BLAST) |
RNAi primary |
|
| External "K07F5.2" Links |
|
| Gene Inhibited |
K07F5.1 (msp-81) |
| Description of "K07F5.1" |
msp-81 encodes a member of the major sperm protein family. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 162
Relative score: 0.478 (Best raw score= for Gene )
Specificity index: 0.068 |
| Wormbase (BLAST) |
RNAi primary |
|
| External "K07F5.1" Links |
|
| Gene Inhibited |
Y59E9AR.1 |
| Description of "Y59E9AR.1" |
Associated GO Term : structural molecule activity |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 68
Specificity index: 0.029 |
| Wormbase (BLAST) |
RNAi secondary |
|
| External "Y59E9AR.1" Links |
|
| Gene Inhibited |
R13H9.2 (msp-57) |
| Description of "R13H9.2" |
msp-57 encodes a member of the major sperm protein family. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 79
Relative score: 0.233 (Best raw score= for Gene )
Specificity index: 0.033 |
| Wormbase (BLAST) |
RNAi secondary |
|
| External "R13H9.2" Links |
|
| Gene Inhibited |
K08F4.8 (msp-38) |
| Description of "K08F4.8" |
msp-38 encodes a member of the major sperm protein family; msp-38 has a C. briggsae homolog as predicted by the Wobble Bulk Aware Bulk Aligner (WABA). |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 111
Relative score: 0.327 (Best raw score= for Gene )
Specificity index: 0.047 |
| Wormbase (BLAST) |
RNAi secondary |
|
| External "K08F4.8" Links |
|
| Gene Inhibited |
T13F2.10 (msp-79) |
| Description of "T13F2.10" |
msp-79 encodes a member of the major sperm protein family. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 155
Relative score: 0.457 (Best raw score= for Gene )
Specificity index: 0.065 |
| Wormbase (BLAST) |
RNAi primary |
|
| External "T13F2.10" Links |
|
| Gene Inhibited |
F32B6.6 (msp-77) |
| Description of "F32B6.6" |
msp-77 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 134
Relative score: 0.395 (Best raw score= for Gene )
Specificity index: 0.056 |
| Wormbase (BLAST) |
RNAi secondary |
|
| External "F32B6.6" Links |
|
| Gene Inhibited |
F58A6.8 (msp-45) |
| Description of "F58A6.8" |
msp-45 encodes a member of the major sperm protein family. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 60
Relative score: 0.177 (Best raw score= for Gene )
Specificity index: 0.025 |
| Wormbase (BLAST) |
RNAi secondary |
|
| External "F58A6.8" Links |
|
| Gene Inhibited |
ZK354.4 (msp-113) |
| Description of "ZK354.4" |
msp-113 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-113 has a C. briggsae homolog as detected by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; the msp-113 promoter region contains two conserved cis elements that are recognition sites for elt-1, a gene that encodes a homolog of the vertebrate GATA transcription factor family; this suggests that a MSP protein is a potential target for ELT-1 in the germ-line; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 65
Relative score: 0.192 (Best raw score= for Gene )
Specificity index: 0.027 |
| Wormbase (BLAST) |
RNAi secondary |
|
| External "ZK354.4" Links |
|
| Gene Inhibited |
ZK354.11 (msp-59) |
| Description of "ZK354.11" |
msp-59 encodes a member of the major sperm protein family. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 80
Relative score: 0.236 (Best raw score= for Gene )
Specificity index: 0.034 |
| Wormbase (BLAST) |
RNAi secondary |
|
| External "ZK354.11" Links |
|
| Gene Inhibited |
T13F2.11 (msp-78) |
| Description of "T13F2.11" |
msp-78 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 166
Relative score: 0.49 (Best raw score= for Gene )
Specificity index: 0.07 |
| Wormbase (BLAST) |
RNAi primary |
|
| External "T13F2.11" Links |
|
| Gene Inhibited |
K05F1.2 (msp-142) |
| Description of "K05F1.2" |
msp-142 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 59 |
| Wormbase (BLAST) |
RNAi secondary |
|
| External "K05F1.2" Links |
|
| Gene Inhibited |
C04G2.4 (msp-36) |
| Description of "C04G2.4" |
msp-36 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family comprises of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSP is involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP assembles into fibrous networks that drives movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 130
Relative score: 0.383 (Best raw score= for Gene )
Specificity index: 0.055 |
| Wormbase (BLAST) |
RNAi primary |
|
| External "C04G2.4" Links |
|
| Gene Inhibited |
ZK1251.6 (msp-76) |
| Description of "ZK1251.6" |
msp-76 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 339
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.143 |
| Wormbase (BLAST) |
RNAi primary |
|
| External "ZK1251.6" Links |
|
| Gene Inhibited |
ZK354.1 (msp-65) |
| Description of "ZK354.1" |
msp-65 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 71
Relative score: 0.209 (Best raw score= for Gene )
Specificity index: 0.03 |
| Wormbase (BLAST) |
RNAi secondary |
|
| External "ZK354.1" Links |
|
| Gene Inhibited |
C04G2.3 |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 154
Relative score: 0.454 (Best raw score= for Gene )
Specificity index: 0.065 |
| Wormbase (BLAST) |
RNAi primary |
|
| External "C04G2.3" Links |
|
| Gene Inhibited |
K07F5.3 (msp-56) |
| Description of "K07F5.3" |
msp-56 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 180
Relative score: 0.531 (Best raw score= for Gene )
Specificity index: 0.076 |
| Wormbase (BLAST) |
RNAi primary |
|
| External "K07F5.3" Links |
|
| Gene Inhibited |
F59A6.8 (msp-71) |
| Description of "F59A6.8" |
msp-71 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 68
Relative score: 0.201 (Best raw score= for Gene )
Specificity index: 0.029 |
| Wormbase (BLAST) |
RNAi secondary |
|
| External "F59A6.8" Links |
|
| Gene Inhibited |
R05F9.13 (msp-31) |
| Description of "R05F9.13" |
msp-31 encodes a member of the major sperm protein family; msp-31 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); expression is enriched in sperm. |
| Evidence for Inhibition |
| Sliding Window |
Raw score: 75
Relative score: 0.221 (Best raw score= for Gene )
Specificity index: 0.032 |
| Wormbase (BLAST) |
RNAi secondary |
|
| External "R05F9.13" Links |
|
| MV_SV:mv_ZK1251.6 Phenotypes |
|
|
| Phenotype |
WTRNAi did not cause viable post-embryonic phenotype
|
| MV_SV:mv_ZK1251.6 Experiment Details |
Ace View |
| Laboratory |
MV |
| RNAi Reagent & Type |
mv_ZK1251.6 (ORFeome_reagent) |
| Remark |
bacterial-feeding RNAi began at the L1 larval stage |
| Reference |
Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...." |
| Delivery Method |
Bacterial_feeding |
| Date |
2004-9-01 |
| Gene Plot of Y59E9AR.7 |
Browse using GBrowse
|
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| Gene Plot of K07F5.2 |
Browse using GBrowse
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| Gene Plot of K07F5.1 |
Browse using GBrowse
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| Gene Plot of Y59E9AR.1 |
Browse using GBrowse
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| Gene Plot of R13H9.2 |
Browse using GBrowse
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| Gene Plot of K08F4.8 |
Browse using GBrowse
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| Gene Plot of F58A6.8 |
Browse using GBrowse
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| Gene Plot of T13F2.10 |
Browse using GBrowse
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| Gene Plot of F32B6.6 |
Browse using GBrowse
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| Gene Plot of ZK354.4 |
Browse using GBrowse
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| Gene Plot of T13F2.11 |
Browse using GBrowse
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| Gene Plot of ZK354.11 |
Browse using GBrowse
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| Gene Plot of K05F1.2 |
Browse using GBrowse
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| Gene Plot of C04G2.4 |
Browse using GBrowse
|
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| Gene Plot of ZK1251.6 |
Browse using GBrowse
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| Gene Plot of ZK354.1 |
Browse using GBrowse
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| Gene Plot of C04G2.3 |
Browse using GBrowse
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| Gene Plot of K07F5.3 |
Browse using GBrowse
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| Gene Plot of R05F9.13 |
Browse using GBrowse
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| Gene Plot of F59A6.8 |
Browse using GBrowse
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