RNAi Experiment: MV_SV:mv_ZK381.1 |
Ace View of MV_SV:mv_ZK381.1
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Genes Inhibited |
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Gene Inhibited |
ZK381.1 (him-3) |
Description of "ZK381.1" |
him-3 encodes a homolog of the S. cerevisiae HOP1 protein which is required for the formation of the synaptonemal complex during meiosis; him-3 is required for synapsis and chiasma formation during meiotic recombination and for chromosome segregation; him-3 mutants show a high frequency of males in the population as well as a high frequency of arrested embryos due to defects in X-chromosome segregation; HIM-3 localizes to the meiotic chromosome associating with both unsynapsed and synapsed chromosomes. |
KOG Annotation  |
HORMA domain
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Evidence for Inhibition |
Sliding Window |
Raw score: 789
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "ZK381.1" Links |
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MV_SV:mv_ZK381.1 Phenotypes |
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Embryonic |
Emb Penetrance None reported |
MV_SV:mv_ZK381.1 Experiment Details |
Ace View |
Laboratory |
MV |
RNAi Reagent & Type |
mv_ZK381.1 (ORFeome_reagent) |
Remark |
bacterial-feeding RNAi began at the L1 larval stage |
Reference |
Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...." |
Delivery Method |
Bacterial_feeding |
Date |
2004-9-01 |
Gene Plot of ZK381.1 |
Browse using GBrowse
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