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RNAi Experiment: MV_SV:mv_ZK381.1 Ace View of MV_SV:mv_ZK381.1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  ZK381.1 (him-3)
Description of "ZK381.1"  him-3 encodes a homolog of the S. cerevisiae HOP1 protein which is required for the formation of the synaptonemal complex during meiosis; him-3 is required for synapsis and chiasma formation during meiotic recombination and for chromosome segregation; him-3 mutants show a high frequency of males in the population as well as a high frequency of arrested embryos due to defects in X-chromosome segregation; HIM-3 localizes to the meiotic chromosome associating with both unsynapsed and synapsed chromosomes.
KOG Annotation  HORMA domain
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 789
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "ZK381.1" Links  Wormbase NCBI
MV_SV:mv_ZK381.1 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
MV_SV:mv_ZK381.1 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_ZK381.1 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of ZK381.1 Browse using GBrowse
Gene Graph