Ace View of PF:GL1_1E9 | |||
Gene Inhibited | C29A12.3 (lig-1) | ||
Description of "C29A12.3" | lig-1 is orthologous to the human gene LIM HOMEOBOX PROTEIN 3 ISOFORM B (LIG1; OMIM:600577), which when mutated leads to disease. | ||
Evidence for Inhibition | |||
External "C29A12.3" Links | |||
Embryonic | Emb Penetrance 100 % | ||
Phenotype | Aberrant cell-cell contacts at the four-cell stage Aberrant nuclear reassembly Ectopic cleavage furrows EMS fails to extend anteriorly Exaggerated asynchrony Excessive blebbing Multiple cavities Multiple nuclei in 1, 2, or 4-cell embryos Nuclei reform next to cell division remnant |
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Movies/Stacks/Images | |||
Laboratory | KK | ||
RNAi Reagent & Type | sjj_C29A12.3 (PCR_reagent) | ||
Remark | PCR product contains flanking T7 promoter sequences | ||
Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | ||
Delivery Method | Injection | ||
Date | 2002-11-19 | ||
Gene Plot of C29A12.3 | |||