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RNAi Experiment: PF:GL1_1E9 Ace View of PF:GL1_1E9
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C29A12.3 (lig-1)
Description of "C29A12.3"  lig-1 is orthologous to the human gene LIM HOMEOBOX PROTEIN 3 ISOFORM B (LIG1; OMIM:600577), which when mutated leads to disease.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:10817513..10818574)
Transcript overlap: 1051 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1051
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C29A12.3" Links  Wormbase NCBI
PF:GL1_1E9 Phenotypes Run Phenoblast! Run Phenoblast Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Phenotype  Aberrant cell-cell contacts at the four-cell stage
Aberrant nuclear reassembly
Ectopic cleavage furrows
EMS fails to extend anteriorly
Exaggerated asynchrony
Excessive blebbing
Multiple cavities
Multiple nuclei in 1, 2, or 4-cell embryos
Nuclei reform next to cell division remnant
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif Help
PF:GL1_1E9 Experiment Details Ace View
Laboratory  KK
RNAi Reagent & Type  sjj_C29A12.3 (PCR_reagent)
Remark  PCR product contains flanking T7 promoter sequences
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Delivery Method  Injection
Date  2002-11-19
Gene Plot of C29A12.3 Browse using GBrowse
Gene Graph