Ace View of PF:GL1_1G7 | |||
Gene Inhibited | C27A2.6 (dsh-2) | ||
Description of "C27A2.6" | dsh-2 encodes a protein containing a DIX domain, a DEP domain, and a PDZ domain that is required for embryonic viability and functions in Wnt pathway signaling between the embryonic blastomeres P2 and EMS with respect to endoderm specification and to orient the division axis of the EMS cell; expressed from the four-cell embryo stage, and is primarily associated with membranes. | ||
KOG Annotation  | Dishevelled 3 and related proteins |
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Evidence for Inhibition | |||
External "C27A2.6" Links | ![]() ![]() |
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Embryonic | Emb Penetrance 50 - 70 % | ||
Larval | Lva
Observed in >=10% of progeny. |
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Adult | Sck
Observed in >=10% of progeny. Stp Observed in >=10% of progeny. |
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Laboratory | KK | ||
RNAi Reagent & Type | sjj_C27A2.6 (PCR_reagent) | ||
Remark | PCR product contains flanking T7 promoter sequences | ||
Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | ||
Delivery Method | Injection | ||
Date | 2002-11-19 | ||
Gene Plot of C27A2.6 | |||
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