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RNAi Experiment: PF:GL1_2C2 Ace View of PF:GL1_2C2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  W01B6.9 (ndc-80)
Description of "W01B6.9"  ndc-80 encodes a member of the HEC/Ndc80p family that affects metaphase plate formation in embryos (thus affecting chromosome segregation), kinetochore-microtubule interactions, locomotion, vulval development, body morphology, and embryonic viability; interacts in vivo with KNL-1, HIM-10, and a homolog of Nuf2p, and NDC-80 and HIM-10 are codependent for kinetochore assembly.
KOG Annotation  Centromere-associated protein HEC1
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:10086863..10087814)
Transcript overlap: 752 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 668
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "W01B6.9" Links  Wormbase NCBI
PF:GL1_2C2 Phenotypes Run Phenoblast! Run Phenoblast Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Phenotype  Abnormal size of pronucleus
Ectopic cleavage furrows
Excessive blebbing
Multiple cavities
Multiple maternal pronuclei
Multiple nuclei in 1, 2, or 4-cell embryos
Pronuclei meet more centrally
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif Help
PF:GL1_2C2 Experiment Details Ace View
Laboratory  KK
RNAi Reagent & Type  sjj_W01B6.9 (PCR_reagent)
Remark  PCR product contains flanking T7 promoter sequences
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Delivery Method  Injection
Date  2002-11-19
Gene Plot of W01B6.9 Browse using GBrowse
Gene Graph