Ace View of PF:GL1_2C2 | |||
Gene Inhibited | W01B6.9 (ndc-80) | ||
Description of "W01B6.9" | ndc-80 encodes a member of the HEC/Ndc80p family that affects metaphase plate formation in embryos (thus affecting chromosome segregation), kinetochore-microtubule interactions, locomotion, vulval development, body morphology, and embryonic viability; interacts in vivo with KNL-1, HIM-10, and a homolog of Nuf2p, and NDC-80 and HIM-10 are codependent for kinetochore assembly. | ||
KOG Annotation  | Centromere-associated protein HEC1 |
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Evidence for Inhibition | |||
External "W01B6.9" Links | |||
Embryonic | Emb Penetrance 100 % | ||
Phenotype | Abnormal size of pronucleus Ectopic cleavage furrows Excessive blebbing Multiple cavities Multiple maternal pronuclei Multiple nuclei in 1, 2, or 4-cell embryos Pronuclei meet more centrally |
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Movies/Stacks/Images | |||
Laboratory | KK | ||
RNAi Reagent & Type | sjj_W01B6.9 (PCR_reagent) | ||
Remark | PCR product contains flanking T7 promoter sequences | ||
Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | ||
Delivery Method | Injection | ||
Date | 2002-11-19 | ||
Gene Plot of W01B6.9 | |||