Link to F46A9.4RNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to F46A9.5.3Link to F46A9.5.2Link to F46A9.5.1geneMap
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RNAi Experiment: PF:GL1_3A2 Ace View of PF:GL1_3A2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F46A9.4 (skr-2)
Description of "F46A9.4"  skr-2 encodes a homolog of Skp1 in S. cerevisiae, a core component of the SCF (Skp1p, Cullin, F-box) ubiquitin-ligase complex that facilitates ubiquitin-mediated protein degradation; SKR-2 is required for the restraint of cell proliferation, progression through the pachytene stage of meiosis, and the formation of bivalent chromosomes at diakinesis; SKR-2::GFP is detected exclusively in the intestine.
KOG Annotation  SCF ubiquitin ligase, Skp1 component
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:9469370..9470527)
Transcript overlap: 622 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 496
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F46A9.4" Links  Wormbase NCBI
PF:GL1_3A2 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 25 - 40 %
Adult  Egl Observed in <10% of progeny.
Gon Observed in <10% of progeny.
PF:GL1_3A2 Experiment Details Ace View
Laboratory  KK
RNAi Reagent & Type  sjj_F46A9.4 (PCR_reagent)
Remark  PCR product contains flanking T7 promoter sequences
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Delivery Method  Injection
Date  2002-11-19
Gene Plot of F46A9.4 Browse using GBrowse
Gene Graph