Link to F10C2.4Link to F10C2.5RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: PF:GL1_3D4 Ace View of PF:GL1_3D4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F10C2.4
Description of "F10C2.4"  F10C2.4 encodes a homolog of the DNA polymerase delta complex subunit A that is required in embryos for the normal timing of embryonic cell divisions (much as DIV-1 is) and, also, for normal chromosome segregation (probably because of defective DNA replication).
KOG Annotation  DNA polymerase delta, catalytic subunit
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:12046868..12047684)
Transcript overlap: 726 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 663
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F10C2.4" Links  Wormbase NCBI
PF:GL1_3D4 Phenotypes Run Phenoblast! Run Phenoblast Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Phenotype  Aberrant cell-cell contacts at the four-cell stage
Aberrant nuclear reassembly
Ectopic cleavage furrows
Exaggerated asynchrony
Excessive blebbing
Multiple cavities
Multiple nuclei in 1, 2, or 4-cell embryos
Nuclei reform next to cell division remnant
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif Help
PF:GL1_3D4 Experiment Details Ace View
Laboratory  KK
RNAi Reagent & Type  sjj_F10C2.4 (PCR_reagent)
Remark  PCR product contains flanking T7 promoter sequences
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Delivery Method  Injection
Date  2002-11-19
Gene Plot of F10C2.4 Browse using GBrowse
Gene Graph