Ace View of PF:GL1_3D4 | |||
Gene Inhibited | F10C2.4 | ||
Description of "F10C2.4" | F10C2.4 encodes a homolog of the DNA polymerase delta complex subunit A that is required in embryos for the normal timing of embryonic cell divisions (much as DIV-1 is) and, also, for normal chromosome segregation (probably because of defective DNA replication). | ||
KOG Annotation  | DNA polymerase delta, catalytic subunit |
||
Evidence for Inhibition | |||
External "F10C2.4" Links | |||
Embryonic | Emb Penetrance 100 % | ||
Phenotype | Aberrant cell-cell contacts at the four-cell stage Aberrant nuclear reassembly Ectopic cleavage furrows Exaggerated asynchrony Excessive blebbing Multiple cavities Multiple nuclei in 1, 2, or 4-cell embryos Nuclei reform next to cell division remnant |
||
Movies/Stacks/Images | |||
Laboratory | KK | ||
RNAi Reagent & Type | sjj_F10C2.4 (PCR_reagent) | ||
Remark | PCR product contains flanking T7 promoter sequences | ||
Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | ||
Delivery Method | Injection | ||
Date | 2002-11-19 | ||
Gene Plot of F10C2.4 | |||