Link to C41G7.1bLink to C41G7.1aLink to C41G7.2.1Link to C41G7.2.2RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to M01E11.6geneMap Link to M01E11.3Link to M01E11.6Link to M01E11.2.1Link to M01E11.2.2RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to C41G7.2.2Link to C41G7.2.1geneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: PF:GL1_3E11 Ace View of PF:GL1_3E11
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C41G7.2 (klp-16)
Description of "C41G7.2"  klp-16 encodes a C-terminal motor kinesin orthologous to the Drosophila melanogaster Ncd and Saccharomyces cerevisiae Kar3; however KLP-16 along with KLP-3, KLP-15 and KLP-17 form an unique subgroup based on amino acid sequence and secondary structure analysis; klp-16 is involved in development of the nervous system in embryos and in chromosome segregation; in situ RNA hybridization experiments indicate that klp-16 is localized in the anterior nervous system in the head region of late embryos.
KOG Annotation  Kinesin (KAR3 subfamily)
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:9513022..9514191)
Transcript overlap: 1075 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1012
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.801
Wormbase (BLAST) RNAi primary
External "C41G7.2" Links  Wormbase NCBI
Gene Inhibited  M01E11.6 (klp-15)
Description of "M01E11.6"  Associated GO Term : microtubule motor activity
KOG Annotation  Kinesin (KAR3 subfamily)
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 252
Relative score: 0.249 (Best raw score= for Gene )
Specificity index: 0.199
Wormbase (BLAST) RNAi secondary
External "M01E11.6" Links  Wormbase NCBI
PF:GL1_3E11 Phenotypes Run Phenoblast! Run Phenoblast Help with Phenotypes
Embryonic  Emb Penetrance 80 - 100 %
Adult  Him >0.4% male progeny observed.
Phenotype  Abnormal size of pronucleus
Multiple cavities
Multiple nuclei in 1, 2, or 4-cell embryos
Polar bodies abnormal
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif Help
PF:GL1_3E11 Experiment Details Ace View
Laboratory  KK
RNAi Reagent & Type  sjj_C41G7.2 (PCR_reagent)
Remark  PCR product contains flanking T7 promoter sequences
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Delivery Method  Injection
Date  2002-11-19
Gene Plot of C41G7.2 Browse using GBrowse
Gene Graph
Gene Plot of M01E11.6 Browse using GBrowse
Gene Graph