Ace View of PF:GL1_3E11 | ||||||
Gene Inhibited | C41G7.2 (klp-16) | |||||
Description of "C41G7.2" | klp-16 encodes a C-terminal motor kinesin orthologous to the Drosophila melanogaster Ncd and Saccharomyces cerevisiae Kar3; however KLP-16 along with KLP-3, KLP-15 and KLP-17 form an unique subgroup based on amino acid sequence and secondary structure analysis; klp-16 is involved in development of the nervous system in embryos and in chromosome segregation; in situ RNA hybridization experiments indicate that klp-16 is localized in the anterior nervous system in the head region of late embryos. | |||||
KOG Annotation  | Kinesin (KAR3 subfamily) |
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Evidence for Inhibition | ||||||
External "C41G7.2" Links | ||||||
Gene Inhibited | M01E11.6 (klp-15) | |||||
Description of "M01E11.6" | Associated GO Term : microtubule motor activity | |||||
KOG Annotation  | Kinesin (KAR3 subfamily) |
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Evidence for Inhibition |
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External "M01E11.6" Links | ||||||
Embryonic | Emb Penetrance 80 - 100 % | |||||
Adult | Him
>0.4% male progeny observed. |
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Phenotype | Abnormal size of pronucleus Multiple cavities Multiple nuclei in 1, 2, or 4-cell embryos Polar bodies abnormal |
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Movies/Stacks/Images | ||||||
Laboratory | KK | |||||
RNAi Reagent & Type | sjj_C41G7.2 (PCR_reagent) | |||||
Remark | PCR product contains flanking T7 promoter sequences | |||||
Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | |||||
Delivery Method | Injection | |||||
Date | 2002-11-19 | |||||
Gene Plot of C41G7.2 | ||||||
Gene Plot of M01E11.6 | ||||||