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RNAi Experiment: PF:GL1_3F3 Ace View of PF:GL1_3F3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C33H5.4 (klp-10)
Description of "C33H5.4"  klp-10 encodes a kinesin-like motor protein that displays similarity to diverse types of kinesin motor domains such as those found in C. elegans OSM-3, the vertebrate CHO1/MKLP proteins, and Saccharomyces cerevisiae Kip3; KLP-10 is required for embryogensis, may play a role in meiosis, and has been implicated in chromosome segregation and cell cycle progression.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:7797741..7798906)
Transcript overlap: 925 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 862
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.569
Wormbase (BLAST) RNAi primary
External "C33H5.4" Links  Wormbase NCBI
Gene Inhibited  C06G3.2 (klp-18)
Description of "C06G3.2"  Associated GO Term : microtubule motor activity
KOG Annotation  Kinesin-like protein
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 653
Relative score: 0.758 (Best raw score= for Gene )
Specificity index: 0.431
Wormbase (BLAST) RNAi primary
External "C06G3.2" Links  Wormbase NCBI
PF:GL1_3F3 Phenotypes Run Phenoblast! Run Phenoblast Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Phenotype  Excessive blebbing
Failure to form pronucleus
Indistinct maternal pronucleus
Loose mitotic furrow
Multiple nuclei in 1, 2, or 4-cell embryos
P0 spindle positioning defect
Paternal pronucleus migrates
Polar bodies abnormal
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif Help
PF:GL1_3F3 Experiment Details Ace View
Laboratory  KK
RNAi Reagent & Type  sjj_C33H5.4 (PCR_reagent)
Remark  PCR product contains flanking T7 promoter sequences
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Delivery Method  Injection
Date  2002-11-19
Gene Plot of C06G3.2 Browse using GBrowse
Gene Graph
Gene Plot of C33H5.4 Browse using GBrowse
Gene Graph