| Ace View of PF:GL1_3F3 | |||||||||
| Gene Inhibited | C33H5.4 (klp-10) | ||||||||
| Description of "C33H5.4" | klp-10 encodes a kinesin-like motor protein that displays similarity to diverse types of kinesin motor domains such as those found in C. elegans OSM-3, the vertebrate CHO1/MKLP proteins, and Saccharomyces cerevisiae Kip3; KLP-10 is required for embryogensis, may play a role in meiosis, and has been implicated in chromosome segregation and cell cycle progression. | ||||||||
| Evidence for Inhibition |
|
||||||||
| External "C33H5.4" Links |   |
||||||||
| Gene Inhibited | C06G3.2 (klp-18) | ||||||||
| Description of "C06G3.2" | Associated GO Term : microtubule motor activity | ||||||||
| KOG Annotation | Kinesin-like protein |
||||||||
| Evidence for Inhibition |
|
||||||||
| External "C06G3.2" Links | |
||||||||
| Embryonic | Emb Penetrance 100 % | ||||||||
| Phenotype | Excessive blebbing Failure to form pronucleus Indistinct maternal pronucleus Loose mitotic furrow Multiple nuclei in 1, 2, or 4-cell embryos P0 spindle positioning defect Paternal pronucleus migrates Polar bodies abnormal |
||||||||
| Movies/Stacks/Images |  |
||||||||
| Laboratory | KK | ||||||||
| RNAi Reagent & Type | sjj_C33H5.4 (PCR_reagent) | ||||||||
| Remark | PCR product contains flanking T7 promoter sequences | ||||||||
| Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | ||||||||
| Delivery Method | Injection | ||||||||
| Date | 2002-11-19 | ||||||||
| Gene Plot of C06G3.2 | |||||||||
 |
|||||||||
| Gene Plot of C33H5.4 | |||||||||
 |
|||||||||
![Adult](JavaScript:void
window.open("/cgi-bin/rnaidb/popUpImage.cgi?imgName=N2wormfinal.png",
"RNAiDB Help","toolbar=no, location=no, directories=no,
status=no, menubar=no, scrollbars=yes, resizable=no,
copyhistory=no, width=1000, height=550"))
 |
Please provide feedback if you are experiencing any difficulties with this website. |