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RNAi Experiment: PF:GL1_4C11 Ace View of PF:GL1_4C11
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F35G12.8 (smc-4)
Description of "F35G12.8"  The smc-4 gene encodes a homolog of the SMC4 subunit of mitotic condensin; SMC-4 acts with MIX-1 to enable chromosome segregation.
KOG Annotation  Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C)
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:4591683..4592857)
Transcript overlap: 1034 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 950
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F35G12.8" Links  Wormbase NCBI
PF:GL1_4C11 Phenotypes Run Phenoblast! Run Phenoblast Help with Phenotypes
Embryonic  Emb Penetrance 80 - 100 %
Larval  Lva Observed in >=10% of progeny.
Phenotype  ABa, ABp and EMS divide synchronously
Aberrant AB or P1 spindle orientation
Cytokinesis defect
Delayed P0 spindle rotation
Division axis of ABa or ABp aberrant
Ectopic cleavage furrows
Multiple cavities
Multiple nuclei in 1, 2, or 4-cell embryos
Nuclei reform next to cell division remnant
P2 and EMS divide synchronously
Pronuclei meet more centrally
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif Help
PF:GL1_4C11 Experiment Details Ace View
Laboratory  KK
RNAi Reagent & Type  sjj_F35G12.8 (PCR_reagent)
Remark  PCR product contains flanking T7 promoter sequences
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Delivery Method  Injection
Date  2002-11-19
Gene Plot of F35G12.8 Browse using GBrowse
Gene Graph