| Ace View of PF:GL1_4C11 | |||||||||
| Gene Inhibited | F35G12.8 (smc-4) | ||||||||
| Description of "F35G12.8" | The smc-4 gene encodes a homolog of the SMC4 subunit of mitotic condensin; SMC-4 acts with MIX-1 to enable chromosome segregation. | ||||||||
| KOG Annotation | Structural maintenance of chromosome protein 4 (chromosome condensation complex Condensin, subunit C) |
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| Evidence for Inhibition |
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| External "F35G12.8" Links |   |
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| Embryonic | Emb Penetrance 80 - 100 % | ||||||||
| Larval | Lva
Observed in >=10% of progeny. |
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| Phenotype | ABa, ABp and EMS divide synchronously Aberrant AB or P1 spindle orientation Cytokinesis defect Delayed P0 spindle rotation Division axis of ABa or ABp aberrant Ectopic cleavage furrows Multiple cavities Multiple nuclei in 1, 2, or 4-cell embryos Nuclei reform next to cell division remnant P2 and EMS divide synchronously Pronuclei meet more centrally |
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| Movies/Stacks/Images |  |
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| Laboratory | KK | ||||||||
| RNAi Reagent & Type | sjj_F35G12.8 (PCR_reagent) | ||||||||
| Remark | PCR product contains flanking T7 promoter sequences | ||||||||
| Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | ||||||||
| Delivery Method | Injection | ||||||||
| Date | 2002-11-19 | ||||||||
| Gene Plot of F35G12.8 | |||||||||
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