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RNAi Experiment: PF:GL1_4C6 Ace View of PF:GL1_4C6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  ZC168.4 (cyb-1)
Description of "ZC168.4"  cyb-1 encodes a cyclin B homolog that appears to be required both for embryogenesis (via maternally encoded CYB-1) and for postembryonic development and fertility (via zygotically encoded CYB-1); removing maternal product in cyb-1(RNAi) embryos causes multiple nuclei, and affected embryos arrest development at an early embryonic stage.
KOG Annotation  Cyclin B and related kinase-activating proteins
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (IV:10735637..10736813)
Transcript overlap: 1008 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 903
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "ZC168.4" Links  Wormbase NCBI
PF:GL1_4C6 Phenotypes Run Phenoblast! Run Phenoblast Help with Phenotypes
Embryonic  Emb Penetrance 80 - 100 %
Larval  Lva Observed in >=10% of progeny.
Adult  Stp Observed in <10% of progeny.
Phenotype  Abnormal size of pronucleus
Division axis of ABa or ABp aberrant
Multiple maternal pronuclei
Multiple nuclei in 1, 2, or 4-cell embryos
Polar bodies abnormal
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif Help
PF:GL1_4C6 Experiment Details Ace View
Laboratory  KK
RNAi Reagent & Type  sjj_ZC168.4 (PCR_reagent)
Remark  PCR product contains flanking T7 promoter sequences
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Delivery Method  Injection
Date  2002-11-19
Gene Plot of ZC168.4 Browse using GBrowse
Gene Graph