Ace View of PF:GL1_4C6 | |||
Gene Inhibited | ZC168.4 (cyb-1) | ||
Description of "ZC168.4" | cyb-1 encodes a cyclin B homolog that appears to be required both for embryogenesis (via maternally encoded CYB-1) and for postembryonic development and fertility (via zygotically encoded CYB-1); removing maternal product in cyb-1(RNAi) embryos causes multiple nuclei, and affected embryos arrest development at an early embryonic stage. | ||
KOG Annotation  | Cyclin B and related kinase-activating proteins |
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Evidence for Inhibition | |||
External "ZC168.4" Links | |||
Embryonic | Emb Penetrance 80 - 100 % | ||
Larval | Lva
Observed in >=10% of progeny. |
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Adult | Stp
Observed in <10% of progeny. |
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Phenotype | Abnormal size of pronucleus Division axis of ABa or ABp aberrant Multiple maternal pronuclei Multiple nuclei in 1, 2, or 4-cell embryos Polar bodies abnormal |
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Movies/Stacks/Images | |||
Laboratory | KK | ||
RNAi Reagent & Type | sjj_ZC168.4 (PCR_reagent) | ||
Remark | PCR product contains flanking T7 promoter sequences | ||
Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | ||
Delivery Method | Injection | ||
Date | 2002-11-19 | ||
Gene Plot of ZC168.4 | |||