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RNAi Experiment: PF:GL1_4D4 Ace View of PF:GL1_4D4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C07H6.5 (cgh-1)
Description of "C07H6.5"  The ortholog of a RNA helicase ste13/ME31B/RCK/p54 that is required for oocyte and sperm function and the prevention of physiological germline-associated apoptosis; it is expressed in the early embryo and germline and localizes to P granules.
KOG Annotation  ATP-dependent RNA helicase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:7496377..7497548)
Transcript overlap: 979 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 916
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C07H6.5" Links  Wormbase NCBI
PF:GL1_4D4 Phenotypes Run Phenoblast! Run Phenoblast Help with Phenotypes
Embryonic  Emb Penetrance 80 - 100 %
Larval  Lva Observed in >=10% of progeny.
Adult  Ste
Stp Observed in >=10% of progeny.
No developing embryos seen 48 hours after dsRNA injection
Reduced fecundity of injected worm
Movies/Stacks/Images  /static/images/movie.gif Help
PF:GL1_4D4 Experiment Details Ace View
Laboratory  KK
RNAi Reagent & Type  sjj_C07H6.5 (PCR_reagent)
Remark  PCR product contains flanking T7 promoter sequences
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Delivery Method  Injection
Date  2002-11-19
Gene Plot of C07H6.5 Browse using GBrowse
Gene Graph