Ace View of PF:GL1_4E2 | |||
Gene Inhibited | AH6.5 (mex-6) | ||
Description of "AH6.5" | mex-6 encodes a CCCH zinc-finger protein highly similar to MEX-5 that functions with MEX-5 to affect embryonic viability, establish soma germline asymmetry in embryos and establish PIE-1, MEX-1, and POS-1 asymmetry in embryos, and also affects formation of intestinal cells; MEX-6 and MEX-5 may act downstream of the PAR proteins. | ||
KOG Annotation  | CCCH-type Zn-finger protein |
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Evidence for Inhibition | |||
External "AH6.5" Links | ![]() ![]() |
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Embryonic | Emb Penetrance 100 % | ||
Phenotype | Aberrant AB or P1 spindle orientation Aberrant cell-cell contacts at the four-cell stage Division axis of ABa or ABp aberrant EMS fails to extend anteriorly P0 spindle positioning defect P2 and EMS divide synchronously Synchronous second division |
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Movies/Stacks/Images | ![]() ![]() ![]() |
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Laboratory | KK | ||
RNAi Reagent & Type | sjj_AH6.5 (PCR_reagent) | ||
Remark | PCR product contains flanking T7 promoter sequences | ||
Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | ||
Delivery Method | Injection | ||
Date | 2002-11-19 | ||
Gene Plot of AH6.5 | |||
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