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RNAi Experiment: PF:GL1_4E9 Ace View of PF:GL1_4E9
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F56H1.4 (rpt-5)
Description of "F56H1.4"  rpt-5 encodes a triple A ATPase subunit of the 26S proteasome's 19S regulatory particle (RP) base subcomplex; RPT-5 is required for embryonic, larval, and germline development and by homology, is predicted to function in unfolding protein substrates and translocating them into the core proteolytic particle (CP) of the proteasome.
KOG Annotation  26S proteasome regulatory complex, ATPase RPT5
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:5742390..5743588)
Transcript overlap: 1031 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 968
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F56H1.4" Links  Wormbase NCBI
PF:GL1_4E9 Phenotypes Run Phenoblast! Run Phenoblast Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Adult  Ste
No developing embryos seen 48 hours after dsRNA injection
Reduced fecundity of injected worm
Phenotype  Catastrophic one-cell arrest
Osmotically/ pressure sensitive
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif Help
PF:GL1_4E9 Experiment Details Ace View
Laboratory  KK
RNAi Reagent & Type  sjj_F56H1.4 (PCR_reagent)
Remark  PCR product contains flanking T7 promoter sequences
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Delivery Method  Injection
Date  2002-11-19
Gene Plot of F56H1.4 Browse using GBrowse
Gene Graph