Link to F39H11.3RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
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RNAi Experiment: PF:GL1_5H4 Ace View of PF:GL1_5H4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F39H11.3 (cdk-8)
Description of "F39H11.3"  cdk-8 encodes a member of the cyclin-dependent serine/threonine protein kinase family orthologous to human CDK8 (OMIM:603184) which functions in transcriptional regulation with the positive regulatory factor cyclin C, is associated with the RNA polymerase II holoenzyme, and may regulate gene-specific activators; CDK-8 also contains a glutamine/asparagine-rich domain; loss of cdk-8 function via RNA-mediated interference (RNAi) results in sterility in the injected hermaphrodite, suggesting that in C. elegans, CDK-8 may play a role in germ-line development.
KOG Annotation  Cyclin C-dependent kinase CDK8
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:8702698..8703895)
Transcript overlap: 792 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 666
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F39H11.3" Links  Wormbase NCBI
PF:GL1_5H4 Phenotypes Help with Phenotypes
Adult  Ste
PF:GL1_5H4 Experiment Details Ace View
Laboratory  KK
RNAi Reagent & Type  sjj_F39H11.3 (PCR_reagent)
Remark  PCR product contains flanking T7 promoter sequences
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Delivery Method  Injection
Date  2002-11-19
Gene Plot of F39H11.3 Browse using GBrowse
Gene Graph