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RNAi Experiment: PF:GL1_6F11 Ace View of PF:GL1_6F11
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  K07C11.2 (air-1)
Description of "K07C11.2"  AIR-1 belongs to the Aurora-A family of serine/threonine kinases that localize to centrosomes; AIR-1 is required for embryonic survival, germline proliferation and development, locomotion, and vulval development; AIR-1 is required to recruit centrosomal gamma-tubulin during maturation; Aurora-A kinases are implicated in centrosome separation and spindle assembly.
KOG Annotation  Serine/threonine protein kinase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:8223879..8225561)
Transcript overlap: 871 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 745
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "K07C11.2" Links  Wormbase NCBI
Gene Inhibited  K07C11.9
KOG Annotation  Uncharacterized conserved protein
What's a KOG?
Evidence for Inhibition 
ePCR Transcript overlap: 20 nt Explain types of evidence for RNAi inhibition
External "K07C11.9" Links  Wormbase NCBI
PF:GL1_6F11 Phenotypes Run Phenoblast! Run Phenoblast Help with Phenotypes
Embryonic  Emb Penetrance 80 - 100 %
Phenotype  Aberrant AB or P1 spindle orientation
Cytokinesis defect
Ectopic cleavage furrows
Exaggerated pseudocleavage
Excessive blebbing
Multiple nuclei in 1, 2, or 4-cell embryos
P0 spindle positioning defect
Polar bodies abnormal
Pronuclei meet more centrally
Synchronous second division
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif Help
PF:GL1_6F11 Experiment Details Ace View
Laboratory  KK
RNAi Reagent & Type  sjj_K07C11.2 (PCR_reagent)
Remark  PCR product contains flanking T7 promoter sequences
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Delivery Method  Injection
Date  2002-11-19
Gene Plot of K07C11.9 Browse using GBrowse
Gene Graph
Gene Plot of K07C11.2 Browse using GBrowse
Gene Graph