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RNAi Experiment: PF:GL1_7D10 Ace View of PF:GL1_7D10
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  D2013.5 (eat-3)
Description of "D2013.5"  The eat-3 gene encodes a mitochondrial dynamin-related protein, closely related to bacterial dynamin-like proteins, that is orthologous to human OPA1 (OMIM:203740, mutated in autosomal dominant optic atrophy); EAT-3 is localized to the mitochondrial matrix and may play a role in regulating inner mitochondrial membrane morphology; EAT-3 is expressed in body wall muscle, intestine, and neurons, all tissues with high metabolic rates.
KOG Annotation  Dynamin-like GTP binding protein
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (II:9328259..9329162)
Transcript overlap: 668 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 605
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "D2013.5" Links  Wormbase NCBI
PF:GL1_7D10 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 20 - 40 % Sle
Larval  Gro Observed in >=10% of progeny.
Adult  Ste
PF:GL1_7D10 Experiment Details Ace View
Laboratory  KK
RNAi Reagent & Type  sjj_D2013.5 (PCR_reagent)
Remark  PCR product contains flanking T7 promoter sequences
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Delivery Method  Injection
Date  2002-11-19
Gene Plot of D2013.5 Browse using GBrowse
Gene Graph