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RNAi Experiment: PF:GL1_7D9 Ace View of PF:GL1_7D9
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F58A4.4 (pri-1)
Description of "F58A4.4"  pri-1 encodes a homolog of the DNA polymerase alpha-primase subunit D that is required in embryos for the normal timing of embryonic cell divisions, much as DIV-1 is.
KOG Annotation  Eukaryotic-type DNA primase, catalytic (small) subunit
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:9612958..9614117)
Transcript overlap: 886 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 781
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.827
Wormbase (BLAST) RNAi primary
External "F58A4.4" Links  Wormbase NCBI
Gene Inhibited  T24C4.5
Description of "T24C4.5"  Associated GO Term : DNA primase activity
Evidence for Inhibition 
Sliding Window Raw score: 163
Relative score: 0.209 (Best raw score= for Gene )
Specificity index: 0.173
Wormbase (BLAST) RNAi secondary
External "T24C4.5" Links  Wormbase NCBI
PF:GL1_7D9 Phenotypes Run Phenoblast! Run Phenoblast Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Phenotype  Division axis of ABa or ABp aberrant
Ectopic cleavage furrows
Exaggerated asynchrony
Excessive blebbing
Large cytoplasmic granules
Multiple cavities
Multiple nuclei in 1, 2, or 4-cell embryos
Nuclei reform next to cell division remnant
Slow cell cycle
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif Help
PF:GL1_7D9 Experiment Details Ace View
Laboratory  KK
RNAi Reagent & Type  sjj_F58A4.4 (PCR_reagent)
Remark  PCR product contains flanking T7 promoter sequences
Reference  Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans"
Delivery Method  Injection
Date  2002-11-19
Gene Plot of T24C4.5 Browse using GBrowse
Gene Graph
Gene Plot of F58A4.4 Browse using GBrowse
Gene Graph