Ace View of PF:GL1_7H9 | |||
Gene Inhibited | F20G4.3 (nmy-2) | ||
Description of "F20G4.3" | nmy-2 encodes a maternally expressed nonmuscle myosin II required for polarized cytoplasmic flow, polarized distribution of the PAR proteins, cytokinesis, and for proper anterior-posterior polarity in early embryos; NMY-2 functions with PAR-5 in the onset of the establishment phase of polarization in the C. elegans zygote along the anterior-posterior axis, and nmy-2 is partially redundant with nmy-1 with respect to embryonic elongation; localization of NMY-2 is dynamic in oocytes and embryos. | ||
KOG Annotation  | Myosin class II heavy chain |
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Evidence for Inhibition | |||
External "F20G4.3" Links | |||
Embryonic | Emb Penetrance 80 - 100 % | ||
Adult | Ste Stp Observed in <10% of progeny. No developing embryos seen 48 hours after dsRNA injection Reduced fecundity of injected worm |
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Laboratory | KK | ||
RNAi Reagent & Type | sjj_F20G4.3 (PCR_reagent) | ||
Remark | PCR product contains flanking T7 promoter sequences | ||
Reference | Piano et al. (2002) Curr Biol "Gene Clustering Based on RNAi Phenotypes of Ovary-Enriched Genes in C. elegans" | ||
Delivery Method | Injection | ||
Date | 2002-11-19 | ||
Gene Plot of F20G4.3 | |||