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RNAi Experiment: PF:ORC_10H5 Ace View of PF:ORC_10H5
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  B0334.11 (ooc-3)
Description of "B0334.11"  ooc-3 encodes a nematode-specific protein with a predicted signal sequence, four predicted transmembrane domains, and two putative PEST sequences; OOC-3 is probably localized to the endoplasmic reticulum (ER), and is maternally required for correct localization of PAR-2 and PAR-3 in the P1 blastomere of the two-cell stage embryo; specifically, OOC-3 is required for restricting PAR-3 to the anterior cortex of the P1 blastomere to assure PAR-2 localization at the posterior cortex; more generally, OOC-3 is required to establish asymmetrical anterior-posterior cortical domains and spindle orientation in P1.
Evidence for Inhibition 
Sliding Window Raw score: 1176
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
External "B0334.11" Links  Wormbase NCBI
PF:ORC_10H5 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 50 - 50 %
PF:ORC_10H5 Experiment Details Ace View
Laboratory  PF
RNAi Reagent & Type  mv_B0334.11 (ORFeome_reagent)
Strain  N2
Delivery Method  Soaking
Gene Plot of B0334.11 Browse using GBrowse
Gene Graph