Link to T24D1.1bLink to T24D1.1aLink to T24D1.2.1Link to T24D1.2.2RNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
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RNAi Experiment: PF:ORC_14F4 Ace View of PF:ORC_14F4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T24D1.1 (sqv-5)
Description of "T24D1.1"  sqv-5 encodes a chondroitin synthase that both initiates and elongates chondroitin chains (unlike human chondroitin synthase, which only elongates them); SQV-5 is required for cytokinesis (e.g., at the one-cell embryo stage), gonad migration, and vulval morphogenesis (by expanding the extracellular space of the vulva in L4 larvae); the common requirement for SQV-5 in both processes may be to promote filling an extracellular space with fluid (either in the eggshell, or underneath the L4 cuticle); SQV-5 colocalizes with SQV-1 at punctate foci (probably the Golgi apparatus) in the cytoplasm of the vulva, the uterus and oocytes; SQV-5 is most similar to human chondroitin synthase (KIAA0990) and Drosophila CG9220.
Evidence for Inhibition 
Sliding Window Raw score: 2069
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
External "T24D1.1" Links  Wormbase NCBI
PF:ORC_14F4 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 20 - 20 %
PF:ORC_14F4 Experiment Details Ace View
Laboratory  PF
RNAi Reagent & Type  mv_T24D1.1 (ORFeome_reagent)
Strain  N2
Delivery Method  Soaking
Gene Plot of T24D1.1 Browse using GBrowse
Gene Graph