RNAi Card Page

RNAi Experiment: PF:ORC_1F4

Genes Inhibited

Gene Inhibited

Description of "F54E12.1"

his-55 encodes an H3 histone; by homology, HIS-55 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-55 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.

Evidence for Inhibition

Sliding Window

Raw score: 366
Relative score: 0.946 (Best raw score= for Gene )
Specificity index: 0.247

External "F54E12.1" Links

Gene Inhibited

F22B3.2 (his-63)

Description of "F22B3.2"

his-63 encodes an H3 histone; by homology, HIS-63 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-63 is a replication-dependent histone locus.

Evidence for Inhibition

Sliding Window

Raw score: 332
Relative score: 0.858 (Best raw score= for Gene )
Specificity index: 0.224

External "F22B3.2" Links

Gene Inhibited

B0035.10 (his-45)

Description of "B0035.10"

his-45 encodes an H3 histone.

Evidence for Inhibition

Sliding Window

Raw score: 387
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.262

External "B0035.10" Links

Gene Inhibited

F17E9.10 (his-32)

Description of "F17E9.10"

his-32 encodes an H3 histone; by homology, HIS-32 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-32 is a replication-dependent histone locus that resides in the HIS5 cluster on chromosome IV.

Evidence for Inhibition

Sliding Window

Raw score: 71
Relative score: 0.183 (Best raw score= for Gene )
Specificity index: 0.048

External "F17E9.10" Links

Gene Inhibited

F08G2.3 (his-42)

Description of "F08G2.3"

his-42 encodes an H3 histone.

Evidence for Inhibition

Sliding Window

Raw score: 74
Relative score: 0.191 (Best raw score= for Gene )
Specificity index: 0.05

External "F08G2.3" Links

Gene Inhibited

T10C6.13 (his-2)

Description of "T10C6.13"

his-2 encodes an H3 histone; his-2 is contained within the histone gene cluster HIS1.

Evidence for Inhibition

Sliding Window

Raw score: 59

External "T10C6.13" Links

Gene Inhibited

F55G1.2 (his-59)

Description of "F55G1.2"

his-59 encodes an H3 histone; by homology, HIS-59 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-59 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.

KOG Annotation

Histones H3 and H4

Evidence for Inhibition

Sliding Window

Raw score: 111
Relative score: 0.287 (Best raw score= for Gene )
Specificity index: 0.075

External "F55G1.2" Links

Gene Inhibited

W09H1.2 (his-73)

Description of "W09H1.2"

his-73 encodes an H3 histone; by homology, HIS-73 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-73 is a replication-dependent histone locus.

Evidence for Inhibition

Sliding Window

Raw score: 138
Relative score: 0.357 (Best raw score= for Gene )
Specificity index: 0.093

External "W09H1.2" Links

PF:ORC_1F4 Phenotypes