RNAi Experiment: PF:ORC_1G7 |
Ace View of PF:ORC_1G7
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Genes Inhibited |
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Gene Inhibited |
C15H11.7 (pas-1) |
Description of "C15H11.7" |
pas-1 encodes a type 6 alpha subunit of the 26S proteasome's 20S protease core particle (CP); PAS-1 is required for embryonic development and by homology, is predicted to comprise the outer rings of the proteasome and to play a role in selective degradation of ubiquitinated proteins during development; in vitro, PAS-1 interacts with VET-1, a coiled-coil domain-containing protein expressed in the early embryo and ATN-1, an alpha-actinin, in addition to other members of the proteasome. |
KOG Annotation  |
20S proteasome, regulatory subunit alpha type PSMA6/SCL1
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Evidence for Inhibition |
Sliding Window |
Raw score: 675
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
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External "C15H11.7" Links |
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PF:ORC_1G7 Phenotypes |
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Embryonic |
Emb Penetrance 100 - 100 % |
Adult |
Ste
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PF:ORC_1G7 Experiment Details |
Ace View |
Laboratory |
PF |
RNAi Reagent & Type |
mv_C15H11.7 (ORFeome_reagent) |
Strain |
N2 |
Delivery Method |
Soaking |
Gene Plot of C15H11.7 |
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