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RNAi Experiment: SA:yk192a11 Ace View of SA:yk192a11
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  ZK617.1 (unc-22)
Description of "ZK617.1"  unc-22 encodes twitchin, a giant intracellular protein with multiple fibronectin- and immunoglobulin-like domains and a single protein kinase domain that is homologous to titin (OMIM:188840); UNC-22 is required in muscle for regulation of the actomyosin contraction-relaxation cycle and for maintenance of normal muscle morphology; UNC-22 associates with myosin and is localized to A-bands; in vitro, UNC-22 can phosphorylate myosin light-chain peptides and can undergo autophosphorylation.
KOG Annotation  Projectin/twitchin and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 2060
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "ZK617.1" Links  Wormbase NCBI
SA:yk192a11 Phenotypes Help with Phenotypes
Adult  Unc %penetrance
SA:yk192a11 Experiment Details Ace View
Laboratory  SA
RNAi Reagent & Type  yk192a11 (cDNA_reagent)
Remark  yk192a11
Reference  Maeda I et al. (2001) Current Biology "Large-scale analysis of gene function in Caenorhabditis elegans by ...."
Date  2001-2-06
Gene Plot of ZK617.1 Browse using GBrowse
Gene Graph