Ace View of SA:yk199a12 | ||||||
Gene Inhibited | Y39G10AL.3 (cdk-7) | |||||
Description of "Y39G10AL.3" | The cdk-7 gene encodes a cyclin-dependent kinase orthologous to human CDK7 (OMIM:601955) that is a component of the general transcription factor IIH (TFIIH) complex; CDK-7 is required during embryogenesis for mRNA transcription and phosphorylation of RNA polymerase II on serine 2 and serine 5, as well as for cell cycle progression, maintenance of ploidy, and completion of meiosis following fertilization. | |||||
KOG Annotation  | Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7 |
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Evidence for Inhibition |
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External "Y39G10AL.3" Links | ||||||
Embryonic | Emb Penetrance 100 % | |||||
Laboratory | SA | |||||
RNAi Reagent & Type | yk199a12 (cDNA_reagent) | |||||
Remark | yk199a12 | |||||
Reference | Maeda I et al. (2001) Current Biology "Large-scale analysis of gene function in Caenorhabditis elegans by ...." | |||||
Date | 2001-2-06 | |||||
Gene Plot of Y39G10AL.3 | ||||||