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RNAi Experiment: SA:yk284g4 Ace View of SA:yk284g4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  K10D6.2
Description of "K10D6.2"  K10D6.2 encodes three isoforms of a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; K10D6.2A-C are worm-specific, with obvious homologs only in C. elegans; K10D6.2A-C are required for embryonic viability in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
Evidence for Inhibition 
Sliding Window Raw score: 1005
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "K10D6.2" Links  Wormbase NCBI
SA:yk284g4 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 96 %
SA:yk284g4 Experiment Details Ace View
Laboratory  SA
RNAi Reagent & Type  yk284g4 (cDNA_reagent)
Remark  yk284g4
Reference  Maeda I et al. (2001) Current Biology "Large-scale analysis of gene function in Caenorhabditis elegans by ...."
Date  2001-2-06
Gene Plot of K10D6.2 Browse using GBrowse
Gene Graph