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RNAi Experiment: SA:yk340g10 Ace View of SA:yk340g10
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  W05E10.3 (ceh-32)
Description of "W05E10.3"  ceh-32 encodes a Six/sine oculis-type homeodomain protein most closely related to the Six3/6 subfamily that contains Drosophila OPTIX and human SIX3 (OMIM:603714, which when mutated leads to holoprosencephaly 2); CEH-32 appears to be essential for development and required for proper head morphogenesis; during embryogenesis, CEH-32 is expressed in hypodermal and neuronal precursors, and at later stages, in the descendants of these cells and in gonadal sheath cells; in some hypodermal cells, ceh-32 is a direct transcriptional target of VAB-3, a PAX-6 ortholog sufficient to induce ceh-32 expression in some cell types and able to bind the ceh-32 promoter in vitro.
KOG Annotation  Transcription factor SIX and related HOX domain proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1698
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "W05E10.3" Links  Wormbase NCBI
SA:yk340g10 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 54 %
Larval  Lva
Adult  Sck
SA:yk340g10 Experiment Details Ace View
Laboratory  SA
RNAi Reagent & Type  yk340g10 (cDNA_reagent)
Remark  yk340g10
Reference  Maeda I et al. (2001) Current Biology "Large-scale analysis of gene function in Caenorhabditis elegans by ...."
Date  2001-2-06
Gene Plot of W05E10.3 Browse using GBrowse
Gene Graph