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RNAi Experiment: SA:yk366g8 Ace View of SA:yk366g8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F35G12.3 (sel-5)
Description of "F35G12.3"  sel-5 encodes a serine/threonine kinase most similar to mammalian GAK1 and Saccharomyces cerevisiae Pak1p; SEL-5 is required for LIN-12/Notch-mediated signaling events that instruct cells of equivalent developmental potential to adopt distinct fates; sel-5 encodes two protein kinase isoforms generated from alternatively spliced mRNAs and appears to influence cell fate decisions by acting before or during ligand-dependent release of the LIN-12 intracellular domain.
KOG Annotation  ARK protein kinase family
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1578
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F35G12.3" Links  Wormbase NCBI
SA:yk366g8 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 22 %
SA:yk366g8 Experiment Details Ace View
Laboratory  SA
RNAi Reagent & Type  yk366g8 (cDNA_reagent)
Remark  yk366g8
Reference  Maeda I et al. (2001) Current Biology "Large-scale analysis of gene function in Caenorhabditis elegans by ...."
Date  2001-2-06
Gene Plot of F35G12.3 Browse using GBrowse
Gene Graph