Ace View of SA:yk386a8 | ||||||
Gene Inhibited | F54A5.3 | |||||
Description of "F54A5.3" | F54A5.3 encodes four proteins by multiple splicing, three of which are rather small (52-81 residues); however, one isoform (F54A5.3A, 316 residues) is a ortholog of vertebrate Shc proteins (e.g., p52/p46SHC and p66SHC); like its orthologs, F54A5.3A has a PTB and an SH2 domain in N- to C-terminal order; F54A5.3 has no obvious function in mass RNAi assays, but might be involved in RAS signal transduction or regulation of apoptosis. | |||||
KOG Annotation  | Adaptor protein SHC and related proteins |
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Evidence for Inhibition |
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External "F54A5.3" Links | ![]() ![]() |
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Phenotype | WT |
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Laboratory | SA | |||||
RNAi Reagent & Type | yk386a8 (cDNA_reagent) | |||||
Remark | yk386a8 | |||||
Reference | Maeda I et al. (2001) Current Biology "Large-scale analysis of gene function in Caenorhabditis elegans by ...." | |||||
Date | 2001-2-06 | |||||
Gene Plot of F54A5.3 | ||||||
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