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RNAi Experiment: SA:yk386a8 Ace View of SA:yk386a8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F54A5.3
Description of "F54A5.3"  F54A5.3 encodes four proteins by multiple splicing, three of which are rather small (52-81 residues); however, one isoform (F54A5.3A, 316 residues) is a ortholog of vertebrate Shc proteins (e.g., p52/p46SHC and p66SHC); like its orthologs, F54A5.3A has a PTB and an SH2 domain in N- to C-terminal order; F54A5.3 has no obvious function in mass RNAi assays, but might be involved in RAS signal transduction or regulation of apoptosis.
KOG Annotation  Adaptor protein SHC and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 885
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F54A5.3" Links  Wormbase NCBI
SA:yk386a8 Phenotypes Help with Phenotypes
Phenotype  WT
SA:yk386a8 Experiment Details Ace View
Laboratory  SA
RNAi Reagent & Type  yk386a8 (cDNA_reagent)
Remark  yk386a8
Reference  Maeda I et al. (2001) Current Biology "Large-scale analysis of gene function in Caenorhabditis elegans by ...."
Date  2001-2-06
Gene Plot of F54A5.3 Browse using GBrowse
Gene Graph