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RNAi Experiment: Simmer:C05D11.3 Ace View of Simmer:C05D11.3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C05D11.3
Description of "C05D11.3"  C05D11.3 encodes an ortholog of APACD (ATP binding protein associated with cell differentiation) conserved in eukaryotes; C05D11.3 has a thioredoxin-like domain, probably lacking catalytic activity; mouse APACD is both cytoplasmic and nuclear, often localized to centrosomes and midbody; C05D11.3 is expressed in all developmental stages, preferentially in neurons and vulva; C05D11.3 is required for normal mitotic spindle formation, pronuclear migration and nuclear-centrosome rotation.
KOG Annotation  ATP binding protein
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:6432048..6433063)
Transcript overlap: 627 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 564
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C05D11.3" Links  Wormbase NCBI
Simmer:C05D11.3 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 50 - 80 %
Adult  Pvl
Unc
Simmer:C05D11.3 Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_C05D11.3 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of C05D11.3 Browse using GBrowse
Gene Graph