RNAi Experiment: Simmer:C23G10.4 |
Ace View of Simmer:C23G10.4
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Genes Inhibited |
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Gene Inhibited |
C23G10.4 (rpn-2) |
Description of "C23G10.4" |
rpn-2 encodes a non-ATPase subunit of the 26S proteasome's 19S regulatory paritcle (RP) base subcomplex; RPN-2 is required for embryonic, larval, and germline development and by homology, is predicted to function in unfolding and recognition of protein substrates and/or recycling of ubiquitin moieties during protein degradation; RPN-2 is expressed sporadically at all stages of development in the pharynx, intestine, body wall muscle, somatic gonad, neurons, and hypodermis. |
KOG Annotation  |
26S proteasome regulatory complex, subunit RPN2/PSMD1
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:6199314..6200382)
Transcript overlap: 973 nt |
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Sliding Window |
Raw score: 910
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "C23G10.4" Links |
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Simmer:C23G10.4 Phenotypes |
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Embryonic |
Emb Penetrance 100 % |
Simmer:C23G10.4 Experiment Details |
Ace View |
Laboratory |
NL |
RNAi Reagent & Type |
sjj_C23G10.4 (PCR_reagent) |
Strain |
NL4256 rrf-3(pk1426) |
Reference |
Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...." |
Date |
2003-10-01 |
Gene Plot of C23G10.4 |
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