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RNAi Experiment: Simmer:C25A11.4:Screen Ace View of Simmer:C25A11.4:Screen
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C25A11.4 (ajm-1)
Description of "C25A11.4"  ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (X:9105342..9106321)
Transcript overlap: 913 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 871
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C25A11.4" Links  Wormbase NCBI
Simmer:C25A11.4:Screen Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Simmer:C25A11.4:Screen Experiment Details Ace View
Laboratory  NL
RNAi Reagent & Type  sjj_C25A11.4 (PCR_reagent)
Strain  NL4256 rrf-3(pk1426)
Reference  Simmer F et al. (2003) PLoS Biology "Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals ...."
Date  2003-10-01
Gene Plot of C25A11.4 Browse using GBrowse
Gene Graph